Contrat Postdoctoral

The Institute of Psychiatry and Neuroscience of Paris is a multi-disciplinary community of over 150 basic and clinical neuroscientists, as well as faculty members working on: Neurodevelopment and Psychiatry, Behavior, Memory and Emotions, Neurovascular system, Multiscale imaging (from molecules to whole brain), Translational Neurosciences and molecular and cellular mechanisms in Aging Brain. Our mission is to : * Understand how the brain works at all levels, from molecular mechanisms to cells, neuronal networks and whole organ through innovative and interdisciplinary research. * Promote the transfer of research and discovery into medical advances for neurological and psychiatric diseases, such as new therapeutics, devices or diagnostics development. * Train the next generation of physicians and scientists to conduct collaborative and creative science. The IPNP of Université Paris and INSERM is settled in a new building constructed adjacent to the Sainte-Anne hospital in the fall 2017. The 4300 m2 new building houses multidisciplinary teams of experts in biology, clinical research, physics, chemistry, engineering and computational science. The IPNP goal is to foster collaborations between basic, translational and clinical research. SITE WEB : https://ipnp.paris5.inserm.fr/english-language POSTE ET MISSIONS The postdoctoral researcher will conduct biochemical and cell biological experiments aimed at characterizing the interactome of a protein involved in membrane trafficking using BioID, co-immunoprecipitation, and confocal microscopy. The project is a collaboration with biotech and will be involved part-time at the company. MOBILITÉ GÉOGRAPHIQUE : Internationale PRISE DE FONCTION : 01/03/2022 PROFIL Strong experience in mammalian cell culture, transfection, biochemistry, cell biology, microscopy required. Ph.D. thesis already obtained. English: written and spoken. OBJECTIFS * BioID interactome in several conditions (pharmacological treatments, expression of perturbing proteins/antibodies) * Characterization of some of the hits